Which Synology models are locked/support only Synology HAT5300 HDD hard drives?

Seagate ironwolf vs HAT5300.   I have project of taking user backup of around 10machine max data is 160TB. so which synlogy and HDD will be better to proposed. RS2421+ only compatible with HAT5300 which is shortage here RS2418+ is available which compatible with other HDD also. so kindly advise which will be best just for backup nothing else. Business 160TB after RAID 6

Synology only forces their drives on XS series NAS models.

RS3621xs+

RS4021xs+

RS1619xs+

Here you can also find Ultrastar and Toshiba.
https://www.synology.com/en-us/compatibility?search_by=products&model=RS2421%2B&category=hdds_no_ssd_trim&p=1&change_log_p=1

I hope this helps.

 

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